BDBM50162964 (11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL363581
SMILES CN(C)C[C@@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21
InChI Key InChIKey=BSOLCASXROXPRZ-SHZHJNINSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50162964
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Inhibition of [3H]-mesulergine binding to human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-pyrilamine binding to human Histamine H1 receptor More data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat Norepinephrine transpoterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 8.60nMAssay Description:Inhibition of [125I]-iodosulpride binding to human Dopamine receptor D3More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of [125I]-R91150 binding to human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to human Dopamine receptor D1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of [3H]-5-HT binding to human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Inhibition of [3H]-rauwolscine binding to Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 78nMAssay Description:Inhibition of [3H]-rauwolscine binding to Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair