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BDBM50163041 5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [1-(2-pyrrolidin-1-yl-ethyl)-1H-indol-6-yl]-amide::CHEMBL176162

SMILES: Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc1ccc2ccn(CCN3CCCC3)c2c1

InChI Key: InChIKey=HAVQSNFOQUEEEC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50163041
PNG
(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Show SMILES Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc1ccc2ccn(CCN3CCCC3)c2c1
Show InChI InChI=1S/C23H24ClN3O2S2/c1-16-20-14-18(24)5-7-22(20)30-23(16)31(28,29)25-19-6-4-17-8-11-27(21(17)15-19)13-12-26-9-2-3-10-26/h4-8,11,14-15,25H,2-3,9-10,12-13H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
109n/an/an/an/an/an/an/an/a



Laboratorios Dr. Esteve S.A.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cells


J Med Chem 48: 1781-95 (2005)


Article DOI: 10.1021/jm049615n
BindingDB Entry DOI: 10.7270/Q2ZP45N9
More data for this
Ligand-Target Pair