BDBM50163223 1-(4-Trifluoromethyl-phenyl)-3-[1-(3-trifluoromethyl-pyridin-2-yl)-pyrrolidin-3-yl]-urea::CHEMBL175763

SMILES FC(F)(F)c1ccc(NC(=O)NC2CCN(C2)c2ncccc2C(F)(F)F)cc1

InChI Key InChIKey=UZLXDYWGWVNJLO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163223   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50163223(1-(4-Trifluoromethyl-phenyl)-3-[1-(3-trifluorometh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human transient receptor potential vanilloid 1 receptor (n=3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50163223(1-(4-Trifluoromethyl-phenyl)-3-[1-(3-trifluorometh...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against human transient receptor potential vanilloid 1 receptor (n=6); InactiveMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50163223(1-(4-Trifluoromethyl-phenyl)-3-[1-(3-trifluorometh...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of rat transient receptor potential vanilloid 1 receptor (n=3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed