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BDBM50163466 CHEMBL3793767

SMILES: Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1

InChI Key: InChIKey=PCKRKAGRGQILDT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163466   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50163466
PNG
(CHEMBL3793767)
Show SMILES Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1
Show InChI InChI=1S/C23H20FN3O2/c1-26-21-12-18(8-9-20(21)25-23(26)16-4-5-16)27-11-10-19(13-22(27)28)29-14-15-2-6-17(24)7-3-15/h2-3,6-13,16H,4-5,14H2,1H3
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KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]-MCH(4-19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 24: 2486-503 (2016)


Article DOI: 10.1016/j.bmc.2016.04.011
BindingDB Entry DOI: 10.7270/Q2862JB1
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50163466
PNG
(CHEMBL3793767)
Show SMILES Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1
Show InChI InChI=1S/C23H20FN3O2/c1-26-21-12-18(8-9-20(21)25-23(26)16-4-5-16)27-11-10-19(13-22(27)28)29-14-15-2-6-17(24)7-3-15/h2-3,6-13,16H,4-5,14H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 24: 2486-503 (2016)


Article DOI: 10.1016/j.bmc.2016.04.011
BindingDB Entry DOI: 10.7270/Q2862JB1
More data for this
Ligand-Target Pair