BDBM50163592 (3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-methoxy-cyclohexyl)-methanone::CHEMBL174588

SMILES CO[C@H]1CC[C@@H](C(=O)c2ccc3nc4c(cc3c2)CCCO4)CC1

InChI Key InChIKey=QOTAQTRFJWLFCR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50163592   

TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataIC50: 0.550nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataIC50: 0.550nMAssay Description:Inhibitory concentration against human metabotropic glutamate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
National Institute of Radiological Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataIC50: 1.21nMAssay Description:Antagonist activity at human mGlu1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163592BDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed