BDBM50163744 (1E,4Z,6E)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl)-7-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one::(1E,6E)-1-(4-Hydroxy-3-methoxy-phenyl)-7-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione::1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione::5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one::CHEMBL179512::cid_5324476::curcumin II::demethoxycurcumin

SMILES: COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)cc2)ccc1O

InChI Key: InChIKey=HJTVQHVGMGKONQ-UHFFFAOYSA-N

Data: 14 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50163744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 33 (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase 1 (Rat)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Intestinal-type alkaline phosphatase (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, germ cell type (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Toll-like receptor 9 (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-lactamase (Pseudomonas aeruginosa)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance protein CDR1 (Yeast)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orphan methyltransferase M.SssI (Spiroplasma monobiae strain MQ-1)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50163744 (demethoxycurcumin | 1-(4-hydroxy-3-methoxyphenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
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