BDBM50163860 CHEMBL3797893::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 16

SMILES: C1CCN(CC1)c2c(c(c(c(c2F)F)S(=O)(=O)N)F)F

InChI Key: InChIKey=VVFJHOCIYNHEFY-UHFFFAOYSA-N

Data: 16 Kd  10 K_off  5 K_on

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50163860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00930	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0290	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0110	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0410	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0710	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0410	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	9.20E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	8.80E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.50E+7	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	2.60E+6	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	1.40E+6	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0710	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0110	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00930	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163860 (carbonic anhydrase (CA) inhibitors, benzenesulphon...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair