BDBM50163863 4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide (2a)::CHEMBL3798446::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 2

SMILES: c1ccc2c(c1)ncn2CC(=O)c3ccc(c(c3)Cl)S(=O)(=O)N

InChI Key: InChIKey=SWJLGRBJIPSPCI-UHFFFAOYSA-N

Data: 23 Kd  12 K_off  6 K_on

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50163863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	3.80E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	6.30E+5	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00750	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00200	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	3.10E+6	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00460	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.140	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.30	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	833	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00460	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Horse)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00200	n/a	n/a	n/a
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Carbonic anhydrase 1 (Rhesus macaque)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.00750	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	3.30E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	7.70E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM50163863 (4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	9.80E+5	n/a	n/a
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