BDBM50164248 3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano-phenyl)-bicyclo[4.1.0]hept-3-yl]-1-[2-((R)-3-hydroxy-pyrrolidin-1-yl)-ethyl]-urea::3-(3-chloro-4-fluorophenyl)-1-((3R,6S)-6-(3-cyanophenyl)bicyclo[4.1.0]heptan-3-yl)-1-(2-((R)-3-hydroxypyrrolidin-1-yl)ethyl)urea::CHEMBL193260

SMILES O[C@@H]1CCN(CCN([C@@H]2CC[C@@]3(CC3C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)C1

InChI Key InChIKey=KJGRXEJUJKUECU-UEELXVCBSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50164248   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164248(3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano...)
Affinity DataKi:  7.90nMAssay Description:Inhibition constant for human Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164248(3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164248(3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164248(3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano...)
Affinity DataKi:  10.7nMAssay Description:Inhibition constant for mouse Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164248(3-(3-Chloro-4-fluoro-phenyl)-1-[(3R,6S)-6-(3-cyano...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition constant for human Melanin concentrating hormone receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed