BDBM50164450 (S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione::CHEMBL370758
SMILES O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)[C@@H]2CCCN12
InChI Key InChIKey=CTZWGZSINBFHFD-FQEVSTJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50164450
Affinity DataKi: 4.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:In vitro inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:In vitro inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cerebral frontal cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 101nMAssay Description:In vitro inhibition of [3H]5-CT binding to 5-hydroxytryptamine 7 receptor in rat hyphalamus membranesMore data for this Ligand-Target Pair
Affinity DataKi: 192nMAssay Description:In vitro inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 976nMAssay Description:In vitro inhibition of [3H]paroxetine binding to 5-hydroxytryptamine transporter in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]GR-113808 binding to 5-hydroxytryptamine 4 receptor of rat striatum membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Inhibition of forskolin-induced increase in cAMP in human 5-hydroxytryptamine 1A receptor expressed HeLa cellsMore data for this Ligand-Target Pair