BDBM50164660 CHEMBL3798481

SMILES c1ccc2c(c1)ccc(n2)C(=O)NO

InChI Key InChIKey=RLBGLCXAYWCPDM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164660   

TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164660(CHEMBL3798481)
Affinity DataIC50: 582nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164660(CHEMBL3798481)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164660(CHEMBL3798481)
Affinity DataIC50: 8.21E+3nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed