BindingDB logo
myBDB logout

BDBM50165022 4-Methyl-2-[3-((1R,5S)-1-methyl-3-aza-bicyclo[3.1.0]hex-3-yl)-1-phenyl-propyl]-phenol::CHEMBL192885

SMILES: Cc1ccc(O)c(c1)C(CCN1C[C@H]2C[C@@]2(C)C1)c1ccccc1

InChI Key: InChIKey=YXRQVWQZHREQJU-VWIBBUNHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165022   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(RAT)
BDBM50165022
PNG
(4-Methyl-2-[3-((1R,5S)-1-methyl-3-aza-bicyclo[3.1....)
Show SMILES Cc1ccc(O)c(c1)C(CCN1C[C@H]2C[C@@]2(C)C1)c1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-8-9-21(24)20(12-16)19(17-6-4-3-5-7-17)10-11-23-14-18-13-22(18,2)15-23/h3-9,12,18-19,24H,10-11,13-15H2,1-2H3/t18-,19?,22+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
118n/an/an/an/an/an/an/an/a



Ranbaxy Research Laboratories

Curated by ChEMBL


Assay Description
Affinity for rat Muscarinic acetylcholine receptor M3


Bioorg Med Chem Lett 15: 2093-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.036
BindingDB Entry DOI: 10.7270/Q2DJ5F4X
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(RAT)
BDBM50165022
PNG
(4-Methyl-2-[3-((1R,5S)-1-methyl-3-aza-bicyclo[3.1....)
Show SMILES Cc1ccc(O)c(c1)C(CCN1C[C@H]2C[C@@]2(C)C1)c1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-8-9-21(24)20(12-16)19(17-6-4-3-5-7-17)10-11-23-14-18-13-22(18,2)15-23/h3-9,12,18-19,24H,10-11,13-15H2,1-2H3/t18-,19?,22+/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
221n/an/an/an/an/an/an/an/a



Ranbaxy Research Laboratories

Curated by ChEMBL


Assay Description
Affinity for rat Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 15: 2093-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.036
BindingDB Entry DOI: 10.7270/Q2DJ5F4X
More data for this
Ligand-Target Pair