BDBM50165109 CHEMBL3798333

SMILES: Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1ccc(cc1)C#N)c1ccc(cc1)C#N

InChI Key: InChIKey=FZBXBBMERJSCLW-UHFFFAOYSA-N

Data: 2 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50165109 (CHEMBL3798333) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1ccc(cc1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C23H18N4O3S/c1-17-2-12-22(13-3-17)31(29,30)27(21-10-6-19(15-25)7-11-21)16-23(28)26-20-8-4-18(14-24)5-9-20/h2-13H,16H2,1H3,(H,26,28)	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jilin University Curated by ChEMBL					Assay Description Inhibition of Gal4-RORgamma-LBD (180 to 507 residues) (unknown origin) expressed in HEK293T cells after 24 hrs by dual-luciferase reporter assay				Eur J Med Chem 116: 13-26 (2016) Article DOI: 10.1016/j.ejmech.2016.03.052 BindingDB Entry DOI: 10.7270/Q2TT4SVK
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50165109 (CHEMBL3798333) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1ccc(cc1)C#N)c1ccc(cc1)C#N Show InChI InChI=1S/C23H18N4O3S/c1-17-2-12-22(13-3-17)31(29,30)27(21-10-6-19(15-25)7-11-21)16-23(28)26-20-8-4-18(14-24)5-9-20/h2-13H,16H2,1H3,(H,26,28)	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jilin University Curated by ChEMBL					Assay Description Displacement of N-terminal biotinylated SRC1-4 coactivator peptide from N-terminal His6-fused human RORgamma-LBD (262 to 507 residues) expressed in E...				Eur J Med Chem 116: 13-26 (2016) Article DOI: 10.1016/j.ejmech.2016.03.052 BindingDB Entry DOI: 10.7270/Q2TT4SVK
					More data for this Ligand-Target Pair