BDBM50165440 2-Amino-5-(3,5-dichloro-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL196235

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=UCKWWQJKSKXTDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165440   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165440(2-Amino-5-(3,5-dichloro-phenylsulfanyl)-6-methyl-3...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165440(2-Amino-5-(3,5-dichloro-phenylsulfanyl)-6-methyl-3...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration against Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165440(2-Amino-5-(3,5-dichloro-phenylsulfanyl)-6-methyl-3...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed