BDBM50165983 CHEMBL3799146

SMILES CSc1sc(c2CC(C)(C)CC(=O)c12)-c1ccn(C)n1

InChI Key InChIKey=CSTVXXHVBSVGJH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165983   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165983(CHEMBL3799146)
Affinity DataKi:  5.58E+3nMAssay Description:Inhibition of GST-tagged human recombinant wild type LRRK2 using fluorescein- ERM as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2017
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165983(CHEMBL3799146)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant LRRK2 G2019S mutant using fluorescein- ERM as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2017
Entry Details Article
PubMed