BDBM50166627 2-(2-Aminomethyl-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL192677

SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1CN

InChI Key InChIKey=MEKGZWQTRCXAFN-OAQYLSRUSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166627   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166627(2-(2-Aminomethyl-phenyl)-N-methyl-N-((S)-1-phenyl-...)
Affinity DataKi:  10nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166627(2-(2-Aminomethyl-phenyl)-N-methyl-N-((S)-1-phenyl-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cytochrome P450 2D6 was determined using MAMC (7-methoxy-4-aminomethyl-coumarin) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50166627(2-(2-Aminomethyl-phenyl)-N-methyl-N-((S)-1-phenyl-...)
Affinity DataEC50:  18nMAssay Description:Agonist activity assessed by ability to stimulate [35S]GTP gammaS binding to opioid receptor kappa in human membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed