BDBM50166903 4-Cyano-N-{(R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide::CHEMBL372205::Lecozotan

SMILES: C[C@H](CN(C(=O)c1ccc(cc1)C#N)c1ccccn1)N1CCN(CC1)c1cccc2OCCOc12

InChI Key: InChIKey=NRPQELCNMADTOZ-UHFFFAOYSA-N

Data: 6 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50166903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile salt export pump (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50166903 (CHEMBL372205 | Lecozotan | 4-Cyano-N-{(R)-2-[4-(2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair