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BDBM50167148 (4R,5R)-5-[(S)-3-(4-Fluoro-phenyl)-1-hydroxy-propyl]-1-methyl-4-phenyl-pyrrolidin-2-one::CHEMBL365024

SMILES: CN1[C@@H]([C@@H](O)CCc2ccc(F)cc2)[C@H](CC1=O)c1ccccc1

InChI Key: InChIKey=JQZGKSBVNFBIJP-WSTZPKSXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167148   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estradiol 17-beta-dehydrogenase 2


(Homo sapiens (Human))
BDBM50167148
PNG
((4R,5R)-5-[(S)-3-(4-Fluoro-phenyl)-1-hydroxy-propy...)
Show SMILES CN1[C@@H]([C@@H](O)CCc2ccc(F)cc2)[C@H](CC1=O)c1ccccc1
Show InChI InChI=1S/C20H22FNO2/c1-22-19(24)13-17(15-5-3-2-4-6-15)20(22)18(23)12-9-14-7-10-16(21)11-8-14/h2-8,10-11,17-18,20,23H,9,12-13H2,1H3/t17-,18+,20-/m1/s1
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Similars

Article
PubMed
n/an/a 1.53E+3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against 17 beta hydroxysteroid dehydrogenase type 2 (type II 17-beta-HSD II)


Bioorg Med Chem Lett 15: 3053-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.025
BindingDB Entry DOI: 10.7270/Q24T6HW8
More data for this
Ligand-Target Pair