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BDBM50167164 (E)-3-{3-[1-(4'-Dimethylamino-biphenyl-4-ylmethyl)-3-isopropyl-ureido]-phenyl}-acrylic acid methyl ester::CHEMBL363132

SMILES: COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1ccc(cc1)N(C)C)C(=O)NC(C)C

InChI Key: InChIKey=NVHMZXLYNDJGQG-WOJGMQOQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167164   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bile acid receptor


(Homo sapiens (Human))
BDBM50167164
PNG
((E)-3-{3-[1-(4'-Dimethylamino-biphenyl-4-ylmethyl)...)
Show SMILES COC(=O)\C=C\c1cccc(c1)N(Cc1ccc(cc1)-c1ccc(cc1)N(C)C)C(=O)NC(C)C
Show InChI InChI=1S/C29H33N3O3/c1-21(2)30-29(34)32(27-8-6-7-22(19-27)11-18-28(33)35-5)20-23-9-12-24(13-10-23)25-14-16-26(17-15-25)31(3)4/h6-19,21H,20H2,1-5H3,(H,30,34)/b18-11+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 162n/an/an/an/a



Universidade de São Paulo

Curated by ChEMBL


Assay Description
Effective concentration against farnesoid X receptor (FXR)


Bioorg Med Chem Lett 15: 3119-25 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.017
BindingDB Entry DOI: 10.7270/Q2125S6Q
More data for this
Ligand-Target Pair