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BDBM50167324 CHEMBL3798055

SMILES: Cc1cn(cn1)-c1ccccc1CN\C(N)=N\C(=O)c1ccc(C[C@H](N)C(O)=O)cc1

InChI Key: InChIKey=KFBMTEGFFFSWBS-LGWFVXIRNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167324   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))
BDBM50167324
PNG
(CHEMBL3798055)
Show SMILES Cc1cn(cn1)-c1ccccc1CN\C(N)=N\C(=O)c1ccc(C[C@H](N)C(O)=O)cc1
Show InChI InChI=1/C22H24N6O3/c1-14-12-28(13-26-14)19-5-3-2-4-17(19)11-25-22(24)27-20(29)16-8-6-15(7-9-16)10-18(23)21(30)31/h2-9,12-13,18H,10-11,23H2,1H3,(H,30,31)(H3,24,25,27,29)/t18-/s2
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Similars

Article
PubMed
n/an/a 5.11E+3n/an/an/an/an/an/a



Karos Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of TPH1 (unknown origin)


Bioorg Med Chem Lett 26: 2855-2860 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.057
BindingDB Entry DOI: 10.7270/Q2SN0BW3
More data for this
Ligand-Target Pair