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BDBM50167380 CHEMBL3798951

SMILES: N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1ccccc1-n1nccn1)C(O)=O

InChI Key: InChIKey=BFURWABQACQVRD-XISACWJONA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))
BDBM50167380
PNG
(CHEMBL3798951)
Show SMILES N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1ccccc1-n1nccn1)C(O)=O
Show InChI InChI=1/C20H21N7O3/c21-16(19(29)30)11-13-5-7-14(8-6-13)18(28)26-20(22)23-12-15-3-1-2-4-17(15)27-24-9-10-25-27/h1-10,16H,11-12,21H2,(H,29,30)(H3,22,23,26,28)/t16-/s2
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Similars

Article
PubMed
n/an/a 335n/an/an/an/an/an/a



Karos Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of TPH1 (unknown origin)


Bioorg Med Chem Lett 26: 2855-2860 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.057
BindingDB Entry DOI: 10.7270/Q2SN0BW3
More data for this
Ligand-Target Pair