BDBM50167489 5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-trione::CHEMBL373311

SMILES CC1(C(=O)NC(=O)NC1=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=LAHYEFDNWASMJY-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50167489   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167489(5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-t...)
Affinity DataKi:  600nMAssay Description:In vitro binding affinity against matrix metalloprotease 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167489(5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-t...)
Affinity DataKi: >2.13E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167489(5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-t...)
Affinity DataKi:  4.02E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167489(5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-t...)
Affinity DataKi: >4.95E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167489(5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed