BDBM50167490 4-{5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-2,4,6-trioxo-hexahydro-pyrimidin-5-yl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL365386
SMILES Cc1cc(COc2ccc(cc2)C2(N3CCN(CC3)C(=O)OC(C)(C)C)C(=O)NC(=O)NC2=O)c2ccccc2n1
InChI Key InChIKey=MUEJBYPIDLKGKN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50167490
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >2.13E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >3.33E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 2More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >4.95E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 1More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >5.02E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 13More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:In vitro inhibitory concentration against human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair