BDBM50167608 (2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189052

SMILES Cc1ccc(F)cc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=MVPVFNYLHBJBHV-XLIONFOSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50167608   

LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  790nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167608((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed