BDBM50168218 4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-m-tolyl-pyran-2-one::CHEMBL275546

SMILES CC(C)c1ccccc1Sc1c(O)cc(oc1=O)-c1cccc(C)c1

InChI Key InChIKey=JWHJBCAUIIRKGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168218   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50168218(4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-m-tolyl...)
Affinity DataIC50: 14nMpH: 4.7Assay Description:Inhibitory activity against purified HIV-1 protease (BH10) at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50168218(4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-m-tolyl...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed