BDBM50168643 3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-(1-{[(thiophen-2-ylmethyl)-amino]-methyl}-cyclohexyl)-piperazin-1-yl]-ethyl}-propionamide::CHEMBL365465

SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)C1(CNCc2cccs2)CCCCC1

InChI Key InChIKey=XQPGJXQZZJHBDT-RUZDIDTESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168643   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168643(3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-...)
Affinity DataKi:  12nMAssay Description:Inhibition of [125I]-AgRP(83132) (radioligand) binding to the hMC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168643(3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of [125I]-NDP-MSH (radioligand) binding to the human MC5R stably expressed in HEK293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168643(3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of [125I]-NDP-MSH (radioligand) binding to the human MC3R stably expressed in HEK293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168643(3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of [125I]-NDP-MSH (radioligand) binding to human MC1R at 10 um concentration stably expressed in HEK293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed