BDBM50168756 (2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-benzenesulfonyl]-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL436277

SMILES C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc3ccncc23)cc1

InChI Key InChIKey=GQVOKPKZCNLEIK-JTHBVZDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168756   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168756((2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-b...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50168756((2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-b...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed