BDBM50169035 1-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL364136::[2',5'-bis-O-(tert-butyldimethylsilyl)-b-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine::[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1', 2'-oxathiole-2',2'-dioxide)thymine

SMILES: Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O

InChI Key: InChIKey=YMSLYTIPSGCZRM-UHFFFAOYSA-N

Data: 6 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50169035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase protein (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50169035 ([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair