BDBM50169050 CHEMBL3806279

SMILES CO[C@@H](C)c1c(NC(=O)Nc2cncc(c2)C(F)(F)F)cnc2cc(C)nn12

InChI Key InChIKey=JOGWVUWPXPMYRQ-JTQLQIEISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169050   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169050(CHEMBL3806279)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of MALT1 C domain (329 to 824 residues) (unknown origin) using Ac-Trp-Leu-Arg-Ser-Arg-Cys(PT14)-NH2 as substrate preincubated for 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169050(CHEMBL3806279)
Affinity DataIC50:  0.0520nMAssay Description:Inhibition of MALT1 (unknown origin) expressed in human Jurkat Clone K22 29Q_H23 cells assessed as IL2 production preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed