BDBM50169462 4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-quinolin-2-yl-[1,2,4]triazol-4-yl}-butylamine::CHEMBL187768

SMILES Cc1cccc2c(CCSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12

InChI Key InChIKey=XFPKKPUAPZGFCK-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50169462   

TargetSomatostatin receptor type 2(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataKi:  1.80nMAssay Description:Inhibitory constant against human sst2 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory constant against human sst5 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataKi:  41nMAssay Description:Binding affinity against human sst3 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataKi:  130nMAssay Description:Binding affinity against human sst1 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataKi:  140nMAssay Description:Binding affinity against human sst4 receptor at a dose of 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataEC50:  34nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50169462(4-{3-[2-(7-Methyl-1H-indol-3-yl)-ethylsulfanyl]-5-...)
Affinity DataEC50:  22nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed