BDBM50169487 CHEMBL426617::[(S)-1-((S)-2-Oxo-piperidin-3-ylaminooxalyl)-pentyl]-carbamic acid 1-[5-(4-fluoro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-2,2-dimethyl-propyl ester

SMILES CCCC[C@H](NC(=O)OC(Cc1nnc(o1)-c1ccc(F)cc1)C(C)(C)C)C(=O)C(=O)N[C@H]1CCCNC1=O

InChI Key InChIKey=AQMZQDJVQGMOQG-NFBCFJMWSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50169487   

TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169487(CHEMBL426617 | [(S)-1-((S)-2-Oxo-piperidin-3-ylami...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of 5 lM Cbz-Phe-Arg-AMC bindign to human cathepsin L activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169487(CHEMBL426617 | [(S)-1-((S)-2-Oxo-piperidin-3-ylami...)
Affinity DataIC50:  650nMAssay Description:Inhibition of 10 lM Cbz-Phe-Arg-AMC binding to human cathepsin K in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169487(CHEMBL426617 | [(S)-1-((S)-2-Oxo-piperidin-3-ylami...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 2 lM Cbz-Phe-Arg-AMC binding to human cathepsin V activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169487(CHEMBL426617 | [(S)-1-((S)-2-Oxo-piperidin-3-ylami...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of 10 lM Cbz-Phe-Arg-AMC binding to human cathepsin B activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169487(CHEMBL426617 | [(S)-1-((S)-2-Oxo-piperidin-3-ylami...)
Affinity DataIC50:  810nMAssay Description:Inhibition of 10 lM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed