BDBM50169743 (13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::(7R,13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::(7R,13S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::(7R,8R,9S,13S,14S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentyldihydrosulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol::CHEMBL1358::FULVESTRANT::Faslodex::Fluvestrant::ICI-182780::US10227334, Fulvestrant::US20240043442, Example Fulvestrant::US20240131013, Compound Fulvestrant::ZD-9238

SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31

InChI Key: InChIKey=VWUXBMIQPBEWFH-UHFFFAOYSA-N

Data: 3 KI  25 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50169743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.813	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0631	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.209	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid hormone receptor ERR1 (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Rat)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid hormone receptor ERR1 (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		1.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		1.39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Human)	BDBM50169743 (CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...) Show SMILES Show InChI	GoogleScholar	UniChem		26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair