BDBM50169808 2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1,1-dimethyl-ethylamino]-propoxy}-benzamide::2-{2-Hydroxy-3-[2-(1H-indol-3-yl)-1,1-dimethyl-ethylamino]-propoxy}-benzonitrile::BUCINDOLOL::CHEMBL321582
SMILES CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1C#N
InChI Key InChIKey=FBMYKMYQHCBIGU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50169808
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against recombinant human Cytochrome P450 2D6 (CYP2D6) after incubated for 45 minutesMore data for this Ligand-Target Pair