BDBM50170622 3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-4-yl)-1-(2-dimethylamino-ethyl)-urea::CHEMBL189147

SMILES CN(C)CCN(C(=O)Nc1ccc(F)c(Cl)c1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key InChIKey=TWIOADNIUSVZGY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170622   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50170622(3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50170622(3-(3-Chloro-4-fluoro-phenyl)-1-(3'-cyano-biphenyl-...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of 5-hydroxytryptamine reuptake by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed