BDBM50170637 2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-phenyl]-1-p-tolyl-ethanol::CHEMBL187709::Triparanol::med.21724, Compound Triparanol

SMILES CCN(CC)CCOc1ccc(cc1)C(O)(Cc1ccc(Cl)cc1)c1ccc(C)cc1

InChI Key InChIKey=SYHDSBBKRLVLFF-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50170637   

TargetC-8 sterol isomerase ERG2(Saccharomyces cerevisiae)
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170637(2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataKi:  2nMAssay Description:Affinity for ERG2 of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170637(2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataKi:  8nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170637(2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataKi:  11nMAssay Description:Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Institut Pasteur Korea

LigandPNGBDBM50170637(2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50:  7.05E+3nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
University Of Bonn

LigandPNGBDBM50170637(2-(4-Chloro-phenyl)-1-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataEC50:  5.28E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed