BDBM50170717 4-(1-Diazo-2,2,2-trifluoro-ethyl)-benzoic acid 2-amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl ester::CHEMBL364546

SMILES Nc1nc2ncc(COC(=O)c3ccc(cc3)[C-]([N+]#N)C(F)(F)F)nc2c(=O)[nH]1

InChI Key InChIKey=AYPJJECBXSRFII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170717   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50170717(4-(1-Diazo-2,2,2-trifluoro-ethyl)-benzoic acid 2-a...)
Affinity DataIC50:  3.74E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50170717(4-(1-Diazo-2,2,2-trifluoro-ethyl)-benzoic acid 2-a...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50170717(4-(1-Diazo-2,2,2-trifluoro-ethyl)-benzoic acid 2-a...)
Affinity DataIC50:  2.09E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed