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BDBM50171000 CHEMBL3805486

SMILES: CN(C)c1ccc2nc(C)c(cc2c1)C1=CCCCC1

InChI Key: InChIKey=XWNJVBAUVHHYGQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171000   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50171000
PNG
(CHEMBL3805486)
Show SMILES CN(C)c1ccc2nc(C)c(cc2c1)C1=CCCCC1
Show InChI InChI=1S/C18H22N2/c1-13-17(14-7-5-4-6-8-14)12-15-11-16(20(2)3)9-10-18(15)19-13/h7,9-12H,4-6,8H2,1-3H3
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Article
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



Michigan State University

Curated by ChEMBL


Assay Description
Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay


Bioorg Med Chem 24: 2441-50 (2016)


Article DOI: 10.1016/j.bmc.2016.04.005
BindingDB Entry DOI: 10.7270/Q2PK0J26
More data for this
Ligand-Target Pair