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BDBM50171003 CHEMBL3805932

SMILES: Cc1ccc2nc(C)c(cc2c1)C1=CCCCC1

InChI Key: InChIKey=URQMDTGPASQGOW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50171003
PNG
(CHEMBL3805932)
Show SMILES Cc1ccc2nc(C)c(cc2c1)C1=CCCCC1
Show InChI InChI=1S/C17H19N/c1-12-8-9-17-15(10-12)11-16(13(2)18-17)14-6-4-3-5-7-14/h6,8-11H,3-5,7H2,1-2H3
PDB
MMDB

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Article
PubMed
n/an/a 8.50E+3n/an/an/an/an/an/a



Michigan State University

Curated by ChEMBL


Assay Description
Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay


Bioorg Med Chem 24: 2441-50 (2016)


Article DOI: 10.1016/j.bmc.2016.04.005
BindingDB Entry DOI: 10.7270/Q2PK0J26
More data for this
Ligand-Target Pair