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BDBM50171055 (3-Ethoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine::CHEMBL426826

SMILES: CCOc1cccnc1Nc1cccc(C)n1

InChI Key: InChIKey=ORDSOSQROZOFQQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171055   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50171055
PNG
((3-Ethoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-am...)
Show SMILES CCOc1cccnc1Nc1cccc(C)n1
Show InChI InChI=1S/C13H15N3O/c1-3-17-11-7-5-9-14-13(11)16-12-8-4-6-10(2)15-12/h4-9H,3H2,1-2H3,(H,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection


Bioorg Med Chem Lett 15: 4350-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.059
BindingDB Entry DOI: 10.7270/Q2QZ29H0
More data for this
Ligand-Target Pair