BDBM50171074 (3-Ethoxy-5-isothiazol-3-yl-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine::CHEMBL198428

SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccsn1

InChI Key InChIKey=LOMSLDJIIXJYGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171074   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171074((3-Ethoxy-5-isothiazol-3-yl-pyridin-2-yl)-(6-methy...)
Affinity DataIC50:  243nMAssay Description:In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detectionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed