BDBM50171318 1-(4-Methoxy-phenyl)-7-methyl-5-(1-propyl-butyl)-4,5-dihydro-1H,3H-1,2a,5,8-tetraaza-acenaphthylen-2-one::CHEMBL190845

SMILES CCCC(CCC)N1CCn2c3c1cc(C)nc3n(-c1ccc(OC)cc1)c2=O

InChI Key InChIKey=SGVFYKDWYYUFDD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171318   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50171318(1-(4-Methoxy-phenyl)-7-methyl-5-(1-propyl-butyl)-4...)
Affinity DataKi:  2nMAssay Description:Binding affinity for corticotropin-releasing factor-1 expressed in leukocyte tyrosine kinase cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50171318(1-(4-Methoxy-phenyl)-7-methyl-5-(1-propyl-butyl)-4...)
Affinity DataIC50:  71nMAssay Description:Inhibition of CRF stimulated cAMP production in CHO cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed