BDBM50171520 (E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichloro-2-fluoro-phenylamino)-quinazolin-6-yl]-amide::CHEMBL190094

SMILES: CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2c1

InChI Key: InChIKey=XDYCDXFDVOBDOO-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair