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BDBM50171576 CHEMBL194521::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-chloro-2-methanesulfonylamino-benzamide

SMILES: CS(=O)(=O)Nc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=SQNUDMNRZZBVKO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171576   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50171576
PNG
(CHEMBL194521 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...)
Show SMILES CS(=O)(=O)Nc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1
Show InChI InChI=1S/C21H24ClN3O5S/c1-31(27,28)24-18-4-3-15(22)11-17(18)21(26)23-16-6-8-25(9-7-16)12-14-2-5-19-20(10-14)30-13-29-19/h2-5,10-11,16,24H,6-9,12-13H2,1H3,(H,23,26)
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PC sid
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Similars

Article
PubMed
n/an/a 560n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells


Bioorg Med Chem Lett 15: 4174-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.089
BindingDB Entry DOI: 10.7270/Q2N29WGN
More data for this
Ligand-Target Pair