BDBM50171925 1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione::1,2-bis(4-bromothiophen-2-yl)ethane-1,2-dione::CHEMBL190672

SMILES Brc1csc(c1)C(=O)C(=O)c1cc(Br)cs1

InChI Key InChIKey=OETIZXGALYTAHK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50171925   

TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  30nMAssay Description:Inhibition constant against human liver carboxylesterase (hCE1) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  30nMAssay Description:Inhibition constant against human liver carboxylesterase (hCE1) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  30.2nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  573nMAssay Description:Inhibition constant against human intestinal carboxylesterase (hiCE) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of 1 mM acetylthiocholine (AcTCh) binding to human AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed