BDBM50172004 (S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid::CHEMBL189110

SMILES CC[C@]1(Cc2cc(OCCCOc3ccc(CC(F)(F)F)cc3Cl)ccc2O1)C(O)=O

InChI Key InChIKey=IUZYEVSRBUMFHK-NRFANRHFSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172004   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataEC50:  2nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataEC50: <1nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataIC50: >1.50E+4nMAssay Description:In vitro binding affinity for PPAR-deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration against human PPAR-gamma in Gal4 transactivation assay; 28% response at 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataEC50:  26nMAssay Description:Effective concentration against hamster PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataIC50: >1.50E+4nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed