BDBM50172075 CHEMBL3808844::US11053225, Positive control (LDC1267)

SMILES: CCOc1cn(nc1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1)-c1ccc(F)cc1C

InChI Key: InChIKey=ISPBCAXOSOLFME-UHFFFAOYSA-N

Data: 18 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50172075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 5 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 8 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fer (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM50172075 (CHEMBL3808844 | US11053225, Positive control (LDC1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair