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BDBM50172289 1-(4-Methoxy-benzenesulfonyl)-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL197407

SMILES: COc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2C)c2ccccc12

InChI Key: InChIKey=IXXUMGONMOKOCS-KRWDZBQOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172289   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50172289
PNG
(1-(4-Methoxy-benzenesulfonyl)-3-((S)-1-methyl-pyrr...)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1cc(C[C@@H]2CCCN2C)c2ccccc12
Show InChI InChI=1S/C21H24N2O3S/c1-22-13-5-6-17(22)14-16-15-23(21-8-4-3-7-20(16)21)27(24,25)19-11-9-18(26-2)10-12-19/h3-4,7-12,15,17H,5-6,13-14H2,1-2H3/t17-/m0/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
19.3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells


Bioorg Med Chem Lett 15: 4780-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.028
BindingDB Entry DOI: 10.7270/Q2RN37DD
More data for this
Ligand-Target Pair