BDBM50172442 (E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-quinolin-6-yl]-3-(4-trifluoromethoxy-phenyl)-acrylamide::CHEMBL196196
SMILES CN(C)CCNc1cc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1
InChI Key InChIKey=ZZOFPJLORHEXGT-IZZDOVSWSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50172442
Affinity DataIC50: 3nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration against human 5-hydroxytryptamine 2C receptor expressed in CHO-K1 cells using [3H]-mesulergineMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]-myo-inositolMore data for this Ligand-Target Pair