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BDBM50172572 CHEMBL196553::N-{4-[3-(4-Ethyl-benzyl)-thioureidomethyl]-2-fluoro-phenyl}-methanesulfonamide

SMILES: CCc1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1

InChI Key: InChIKey=ALRXYYQBPBHIDV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172572   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vanilloid receptor


(Rattus norvegicus (rat))
BDBM50172572
PNG
(CHEMBL196553 | N-{4-[3-(4-Ethyl-benzyl)-thioureido...)
Show SMILES CCc1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1
Show InChI InChI=1S/C18H22FN3O2S2/c1-3-13-4-6-14(7-5-13)11-20-18(25)21-12-15-8-9-17(16(19)10-15)22-26(2,23)24/h4-10,22H,3,11-12H2,1-2H3,(H2,20,21,25)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes


J Med Chem 48: 5823-36 (2005)


Article DOI: 10.1021/jm0502790
BindingDB Entry DOI: 10.7270/Q2057FGN
More data for this
Ligand-Target Pair