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BDBM50172982 4-[3-Oxo-4-(2-pyridin-1-yl-ethyl)-3,4-dihydro-quinoxalin-2-ylamino]-N-thiophen-2-ylmethyl-benzamide::CHEMBL372478

SMILES: O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCc3ccccn3)c2=O)cc1

InChI Key: InChIKey=FGVRHLFLOPXFFD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172982   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscle glycogen phosphorylase


(Homo sapiens (Human))
BDBM50172982
PNG
(4-[3-Oxo-4-(2-pyridin-1-yl-ethyl)-3,4-dihydro-quin...)
Show SMILES O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCc3ccccn3)c2=O)cc1
Show InChI InChI=1S/C27H23N5O2S/c33-26(29-18-22-7-5-17-35-22)19-10-12-21(13-11-19)30-25-27(34)32(16-14-20-6-3-4-15-28-20)24-9-2-1-8-23(24)31-25/h1-13,15,17H,14,16,18H2,(H,29,33)(H,30,31)
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Article
PubMed
n/an/a 580n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase of rabbit muscle


Bioorg Med Chem Lett 15: 4790-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.021
BindingDB Entry DOI: 10.7270/Q2125TF8
More data for this
Ligand-Target Pair